Wednesday, May 5, 2021

SARS-CoV-2 Spike Protein Causes Vascular Damage Even When Rest of Virus Removed

 

The Salk Institute publicized a recent study on their website that found that the spike protein of SARS-CoV-2 causes biological damage to our bodies even in the absence of the rest of the virus' RNA:

The novel coronavirus’ spike protein plays additional key role in illness. April 30, 2021 https://www.salk.edu/news-release/the-novel-coronavirus-spike-protein-plays-additional-key-role-in-illness/

Salk researchers and collaborators show how the protein damages cells, confirming COVID-19 as a primarily vascular disease

In the new study, the researchers created a “pseudovirus” that was surrounded by SARS-CoV-2 classic crown of spike proteins, but did not contain any actual virus. Exposure to this pseudovirus resulted in damage to the lungs and arteries of an animal model—proving that the spike protein alone was enough to cause disease. Tissue samples showed inflammation in endothelial cells lining the pulmonary artery walls.

The team then replicated this process in the lab, exposing healthy endothelial cells (which line arteries) to the spike protein. They showed that the spike protein damaged the cells by binding ACE2. This binding disrupted ACE2’s molecular signaling to mitochondria (organelles that generate energy for cells), causing the mitochondria to become damaged and fragmented.

Previous studies have shown a similar effect when cells were exposed to the SARS-CoV-2 virus, but this is the first study to show that the damage occurs when cells are exposed to the spike protein on its own.

The published study is available here: 

Lei et al. (2021, March 31). SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2. Circulation Research, 128:1323–1326 https://doi.org/10.1161/CIRCRESAHA.121.318902

 

What are the implications for vaccinations (plural here not simply singular)?

What are the implications for antibody enhancement?

 


10 comments:

  1. Apologies for being so slow to update comments. I hope to be faster this summer when the work pressure is less.

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  2. Crape technology counterpunch

    But the science of developmental biology (which is different from the microbial and biochemical sciences that came up with CRISPR technology) has shown again and again that embryos simply cannot be reliably engineered. The confusions and misinformation that inevitably accompany the manufactured need for these questionable procedures is not allayed by the futuristic pondering in the books discussed in the NYRB piece, which offer nothing to help the buyer to beware in what the reviewer unskeptically calls the “genetic supermarket.”

    ReplyDelete
  3. People take in on a daily basis more Radionuclide mutagens and carcinogens. More heavy metal and pesticide poisons than u wanna admit. They can't even get crspr right, and u want to niggle and persevere over nucleic acids, amino acids, and protein . Crazy person. Like the psychotic criminal, racist-liar stock and it's buddies

    ReplyDelete
  4. https://www.counterpunch.org/2021/05/03/gop-still-wants-to-pretend-the-preservation-of-slavery-wasnt-a-major-reason-for-the-american-revolution/

    ReplyDelete
  5. I am very pessimistic about our outlook. Especially if america does not change drastically, soon. We would all be dead by August if trump had stayed in power. That is how bad he was. A wreckles, imbecile, psychopathth and criminal.killer. There probably would have been a nuke bomb used by him or he would have caused a few major nuclear accidents singlehandedly. A menace and mass murder, liar. I won't compare him to other presidents because they are bad as chomsky says. Yet even chomsky says that trump is the most imbecilic dangerous thing in history. The hip is now a nazi party and the corporate democreeps fascist imperialists. Maybe 4 or five years left. I do not know why media continues to pay attention to an abomination and killer like suko but they do. https://www.alternet.org/2021/05/mcconnell-destroy-gop/

    Maybe u can sik the criminal murderer stock on me majia. He can put me.out of my ptsd migraine nightmare misery. I'm sure he would oblige he has been threatening to for years.that thing is the most crass demon I have ever encountered he can pay a stooge to kill me or something else that thing is an evil.monster. sadism.tortur3 hate fear is the crux of their existence

    ReplyDelete
  6. https://www.counterpunch.org/2021/05/06/chauvin-lost-but-the-murderers-won/

    ReplyDelete
  7. All nuclear states, are totalitarian abominations. Usa, russia, china, the smaller ones, are fascist devil's. The usa is the worst and the racist trash, whites, in the usa which is half the whites, wanna make the totalitarianism and insanity worse. Racist-mass incarceration nuclear abomination evil, USA worst. The nazi repuklicans and trump butts, want a syphilitic moron, mass murderer back in power. They wany active gestapo in the streets, mass concentration camps. Mass death and arrests. Christian fascists, racists . 4 million already in jail . They exploded so many nuclear bombs on their own people. Million or more homeless.

    https://youtu.be/c4tXo8CfGGo. Conrad miller on wat is really going on in japan murican evil nuclear client state


    Gammas, alpha, x-rays, cosmic rays, beta, go right after dna and chromosomes. They attack and destroy strands, linkages, chemical bonds, in the most basic level.all the fools stistical bullshit cannot change that. They throw statistical be and lies me, can't deny these basic mechanisms and truths. Ionizing radiation is the most mutagenic phenomina known in therms of repetitive and malignant destruction of cel nuclei dna breakage chromosome damage and mutation . The basis for the most dna and chromosomes damage, in the world now. I could say, that the Radionuclide pollution in cities accounts, for 10000 cases of verifiable cancer per year in the cities from Radionuclide from car exhaust and other source. The valley fever that crazy majia got from the effects of radioactive smoke on her ungs and immune system. They can't have a nazi civil war like the whites want because all their decrepit shitty nuclear reactors will start exploding. Americans are a brainwashed rationalizing bunch. The nucleoapes especially want to keep getting, their blood money no matter what. They murdered karen silkwood. The american and japanese fascist powers that be would have you me offed if they thought you or I were a substantial threat however subtly it seemed u died. In the end, like 1984 or the grand inquisition. They would have you renounce your heresy, as they tortured you and murdered you.

    ReplyDelete
  8. CANADA ONE OF THE WORST NUCLEOAPE COUNTRIES. GEEZ I WONDER WHAT IT COULD BE THEY WILL NEVER TELL YOU THEY ARE EVIL DEVILS

    https://futurism.com/mysterious-brain-disease-spreading-canada/amp?__twitter_impression=true
    A Mysterious Brain Disease Is Spreading in Canada
    Victor Tangermann in NeoscopeNeuroscience/Brain Science
    The Canadian province of New Brunswick is tracking 48 cases of a mysterious new brain disease that has neurobiologists stumped, the BBC reports.

    The Canadian province of New Brunswick is tracking 48 cases of a mysterious new brain disease that has neurobiologists stumped, the BBC reports.

    The patients, with ages ranging from 18 to 85,

    ReplyDelete
  9. And idiots wonder why so many refugees flock to the usa from a and central america. It's from the fascist fs america installs there

    https://www.counterpunch.org/2021/05/07/colombia-on-the-brink/

    This is to the hippocritical idiot CIA agent cecalli helper who lives off social security in uraguay and loves the fascists that wanna screw Venezuela the fascists in Guatemala Honduras Columbia etc

    https://www.counterpunch.org/2021/05/07/colombia-on-the-brink/

    ReplyDelete
  10. https://www.commondreams.org/news/2021/05/06/doj-warns-gop-led-arizona-election-audit-may-violate-civil-rights-law

    FASCIST BASTARDS IN BRAZIL MASSACRE 25 INNOCENTS
    THESE ARE THE SORT OF THINGS EVIL DEVIL MURDERERous criminals LIKE THE STOCK and trump LOVE

    https://www.commondreams.org/news/2021/05/07/was-massacre-brazilian-police-kill-two-dozen-deadliest-favela-raid-rios-history

    ReplyDelete