Friday, July 31, 2020

Covid-19: A Global Threat to the Nervous System

Direct excerpt:
Koralnik, I.J. and Tyler, K.L. (2020), COVID ‐19: A Global Threat to the Nervous System. Ann Neurol, 88: 1-11. doi:10.1002/ana.25807

ABSTRACT: In less than 6 months, the severe acute respiratory syndrome‐coronavirus type 2 (SARS‐CoV‐2) has spread worldwide infecting nearly 6 million people and killing over 350,000. 
Initially thought to be restricted to the respiratory system, we now understand that coronavirus disease 2019 (COVID‐19) also involves multiple other organs, including the central and peripheral nervous system. 
The number of recognized neurologic manifestations of SARS‐CoV‐2 infection is rapidly accumulating. These may result from a variety of mechanisms, including virus‐induced hyperinflammatory and hypercoagulable states, direct virus infection of the central nervous system (CNS), and postinfectious immune mediated processes. 
Example of COVID‐19 CNS disease include encephalopathy, encephalitis, acute disseminated encephalomyelitis, meningitis, ischemic and hemorrhagic stroke, venous sinus thrombosis, and endothelialitis. In the peripheral nervous system, COVID‐19 is associated with dysfunction of smell and taste, muscle injury, the Guillain‐Barre syndrome, and its variants. 
Due to its worldwide distribution and multifactorial pathogenic mechanisms, COVID‐19 poses a global threat to the entire nervous system. Although our understanding of SARS‐CoV‐2 neuropathogenesis is still incomplete and our knowledge is evolving rapidly, we hope that this review will provide a useful framework and help neurologists in understanding the many neurologic facets....

Covid-19 is the unexpected crisis that is crowning the triple-crown of the 2007-2008 financial crisis, the 2010 BP oil spill, and the 2011 Fukushima disaster.

Each of these disasters wrecked social, economic and ecological lives and livelihoods.

Now we are vulnerable and exposed to the crowning, novel coronavirus crisis: SARS-CoV-2.

Existing infrastructural vulnerabilities - such as the hurricanes ripping up the southeast US - are going to be amplified as congregated workers get sick.

Seat belt on.



    1. The trolls are only interested in posting propagangda for the fascist regime. There has been good info here in what is left of free media . Things are getting dark. I wonder how much long free dissent will last with secret police goons on our streets.

  2. Too bad that hydroxychloroquine turned out to be one of those drugs that has been around for decades and was not detected as very, very dangerous! One wonders why the eminent doctor Harvey Risch of Yale would recommend it? There are pharmacists all over the USA that know HCQ is lethal. Unfortunately there simply is nothing one can do but sequester and wait for the Bill Gates vaccine! Meanwhile wear that mask even at home even if you live alone. Consider getting some goggles. Wash down with alcohol. Also if you have always wondered about drug addiction and alcoholism . . . you may find out.

    1. That is one of the most psychotic comments, I have ever read.

    2. You need to take a refresher course on abnormal psychology.

    3. St. George thinks he is a good actor. He thinks he fools people but, we all know he is a demented old psychotic asshole.


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