Sunday, July 29, 2012

Fluoridated Water Correlated with Lower IQ


hat tip: The Watchers: http://thewatchers.adorraeli.com/2012/07/28/major-harvard-study-confirms-fluoride-lowers-childrens-iq/


Majia here: This is the second study I've seen correlating fluoride in water with lower IQs in children. When I mentioned the first study to my dentist, he could not  believe it. It is dogma among many dentists that fluoride is necessary for strong teeth. 

After reading the abstract below, you may want to get the back story on how fluoride ended up in our water supply. A good source for background on fluoride in our water:

The Fluoride Deception: How a Nuclear Waste Byproduct Made Its Way Into the Nation’s Drinking Water http://www.democracynow.org/2004/6/17/the_fluoride_deception_how_a_nuclear

 
NEW STUDY LIKING FLUORIDE AND LOWER IQ
 
Developmental Fluoride Neurotoxicity: A Systematic Review and Meta-Analysis
Anna L. Choi, Guifan Sun, Ying Zhang, Philippe Grandjean
 http://ehp03.niehs.nih.gov/article/fetchArticle.action;jsessionid=5C98A897B69464FD44D98698EE9FC4A1?articleURI=info%3Adoi%2F10.1289%2Fehp.1104912

[Abstract] Background: Although fluoride may cause neurotoxicity in animal models and acute fluoride poisoning causes neurotoxicity in adults, very little is known of its effects on children’s neurodevelopment.

Objective: We performed a systematic review and meta-analysis of published studies to investigate the effects of increased fluoride exposure and delayed neurobehavioral development.

Methods: We searched the MEDLINE, EMBASE, Water Resources Abstracts, and TOXNET databases through 2011 for eligible studies. We also searched the China National Knowledge Infrastructure (CNKI) database, as many studies on fluoride neurotoxicity have been published in Chinese journals only. In total, we identified 27 eligible epidemiological studies with high and reference exposures, endpoints of IQ scores or related cognitive function measures with means and variances for the two exposure groups. We estimated the standardized mean difference (SMD) between exposed and reference groups across all studies using random effects models. We conducted sensitivity analyses restricted to studies using the same outcome assessment and having drinking water fluoride as the only exposure. Cochran test for heterogeneity between studies, Begg’s funnel plot and Egger test to assess publication bias were performed. Meta-regressions to explore sources of variation in mean differences among the studies were conducted.

Results: The standardized weighted mean difference in IQ score between exposed and reference populations was -0.45 (95% CI -0.56 to -0.35) using a random-effects model. Thus, children in high fluoride areas had significantly lower IQ scores than those who lived in low fluoride areas. Subgroup and sensitivity analyses also indicated inverse associations, although the substantial heterogeneity did not appear to decrease.

Conclusions: The results support the possibility of an adverse effect of high fluoride exposure on children’s neurodevelopment. Future research should include detailed individual-level information on prenatal exposure, neurobehavioral performance, and covariates for adjustment.
 
Citation: Choi AL, Sun G, Zhang Y, Grandjean P 2012. Developmental Fluoride Neurotoxicity: A Systematic Review and Meta-Analysis. Environ Health Perspect :-. http://dx.doi.org/10.1289/ehp.1104912

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