Thursday, October 1, 2020

Will Covid-19 Damage My Heart?

 

In late January and early February 2020 I encountered "whistleblowing" about SARS-CoV-2 and the disease it produces, Covid-19.

At the time I didn't know whether the information I came across was misinformation or authentic.

However, since that time, almost all of the claims about the disease made in those early comments have been empirically substantiated:

  1. Disease can be transmitted by asymptomatic carriers
  2. Virus is persistent on surfaces and in aerosols
  3. Recovery from the virus is not complete. Virus may be chronic or dormant, like Hepatitis A or Herpes and may cause "silent" damage.
  4. Reinfection can occur (because of RNA mutations) with each one threatening host even more, especially with antibody enhancement effect
  5. Virus circulates inside of body and attacks organs such as the heart, liver, kidneys, etc.
  6. Virus reduces viable sperm and can complicate late pregnancy

From these early accounts, I created a BETA-CORONAVIRUS COLLAPSE DISORDER scenario based in 3 risk indicators:

  • Reinfection potential
  • Post-viral syndrome and/or other severe morbidities
  • Failed social response

The evidence for each of these risk indicators is flashing orange. The question of the pervasiveness of reinfection and morbidities remains unknown but the evidence growing around cardiac effects is entirely alarming:

Yancy CW, Fonarow GC. Coronavirus Disease 2019 (COVID-19) and the Heart—Is Heart Failure the Next Chapter? JAMA Cardiol. Published online July 27, 2020. doi:10.1001/jamacardio.2020.3575

...Months after a COVID-19 diagnosis, the possibility exists of residual left ventricular dysfunction and ongoing inflammation, both of sufficient concern to represent a nidus for new-onset heart failure and other cardiovascular complications. 

Moreover, we cannot dismiss important other clinical pathophysiological observations, including clinical syndromes consistent with acute myocarditis, the cascade of immunologic responses, a prothrombotic milieu with microvascular clot formation, and/or myocardial injury due to supply-demand mismatch. 

When added to the postmortem pathological findings from Linder et al,4 we see the plot thickening and we are inclined to raise a new and very evident concern that cardiomyopathy and heart failure related to COVID-19 may potentially evolve as the natural history of this infection becomes clearer.


Does "the natural history of this virus" destroy the viability of the human heart?

What is the natural history of a virus? According to the CDC's online introduction to epidemiology https://www.cdc.gov/csels/dsepd/ss1978/lesson1/section9.html
Natural history of disease refers to the progression of a disease process in an individual over time, in the absence of treatment. 
For example, untreated infection with HIV causes a spectrum of clinical problems beginning at the time of seroconversion (primary HIV) and terminating with AIDS and usually death. It is now recognized that it may take 10 years or more for AIDS to develop after seroconversion.(43
Many, if not most, diseases have a characteristic natural history, although the time frame and specific manifestations of disease may vary from individual to individual and are influenced by preventive and therapeutic measures. 

I certainly hope that cardiac and other organ damage ARE NOT the natural history of covid-19 but don't expect to be told explicitly by the CDC. I hope you were all SHOCKED and DISGUSTED by the agency's willingness to compromise children's safety in schools by minimizing representations of kids getting and transmitting covid-19. Read about it here:https://www.nytimes.com/2020/09/28/us/politics/white-house-cdc-coronavirus-schools.html


Dr. Fauci warned us in July about a post viral syndrome. This may be it. I sure hope not....


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